Posts Tagged ‘AstraZeneca’

Semantic Web Jobs: AstraZeneca

AstraZeneca_LogoAstraZeneca is looking for an Associate Life Science Architect Solutions Engineer in Waltham, MA. According to the post, “The RDI organization is seeking outstanding candidates to develop and implement algorithms and software for the management and exploitation of biomedical data to advance drug R&D. Working at the interface of cutting-edge science and biomedical data science, the candidate should have skills in both algorithm development as well as software development with a background or interest in biomedical research. The candidate would work with a highly multi-disciplinary staff to design, investigate and evaluate competing algorithm solutions, lead the software and algorithm development, and effectively communicate the results for internal audiences, as well as for publication. The candidate should be motivated to work with minimal supervision and be able to independently identify creative solutions to obstacles.” Read more

Daedalus Takes Meaning-As-A-Service To Excel, GATE And CMS Systems

meaningasaserviceDaedalus (which The Semantic Web Blog originally covered here) has just made its Textalytics meaning-as-a-service APIs available for Excel and GATE (General Architecture for Text Engineering), a JAVA suite of tools used for natural language processing tasks, including information extraction in many languages. Connecting its semantic analysis tools with these systems is one step in a larger plan to extend its integration capabilities with more API plug-ins.

“For us, integration options are a way to lower barriers to adoption and to foster the development of an ecosystem around Textalytics,” says Antonio Matarranz, who leads marketing and sales for Daedalus. The three main ecosystem scenarios, he says, include personal productivity tools, of which the Excel add-in is an example, and NLP environments, of which GATE is an example. “But UIMA (Unstructured Information Management Applications) is also a target,” he says. The list also is slated to include content management systems and search engines, among them open source systems like WordPress, Drupal, and Elasticsearch.

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Clinical Studies And The Road To Linked Data

Clinical studies aren’t what they used to be. In the past, the process was one-off: You conducted a study, gathered a lot of data, analyzed it, wrote a report, and submitted it to the authorities. But, says long-time Linked Data advocate Kerstin Forsberg, an information architect at AstraZeneca, that’s all changed in the last few years.

“A study is not a study on its own,” says Forsberg. Today, the goal is  to do meta-analysis across many studies, so parties ranging from  pharmaceuticals companies to contract research organizations to government authorities all are ‘customers’ of clinical data, so to speak. Data from various studies must be shared among all these parties. “It puts a new context around clinical trial data, that it must be easy to link data together, to link across several different studies,” she says.

The case is there to use modern information standards, like semantic web standards and Linked Data principles, to address this need. It’s why Forsberg is one of the individuals spearheading a volunteer effort to create RDF and OWL representations of the standards published by the Clinical Data Interchange Standards Consortium (CDISC) an international, non-profit organization that develops and supports global data standards for medical research.

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Pharma Becoming Ever-Bigger Fan of Semantic Technology

Courtesy: Flickr/

At the Semantic Technology and Business Conference in New York City last week, attendees got to hear a lot about how semantic technology is influencing various sectors, such as government (see our stories here and here) and media (see this article and this one). Another prominent one on display: pharmaceuticals.

Pharma, for example, was the driving use case for the update to Callimachus that focuses on helping users deal with data that’s external to the framework for data-driven applications, David Wood, CTO of Callimachus project sponsor 3 Round Stones, told The Semantic Web Blog at the event. (To learn more about the update, see our story here.)

A session on Tuesday last week saw Lee Feigenbaum, vp of marketing at Cambridge Semantics, which makes the Anzo express and Anzo Enterprise solutions,  put forth a case for semantic tech as being key to data integration and interoperability in the sector, as well. “Can semantic web technologies break down enterprise data silos just as they break down document silos on the web?” he said. “The answer to the question is, “Of course.” Compared to the web, the data silo challenges of even the largest pharmaceuticals organization is relatively minor.”

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Semantic Models for CDISC

Kerstin Forsberg has written an article discussing a presentation she and Frederik Malfait gave regarding the use of semantic models for CDISC-based standard and metadata management, pointing to case studies at AstraZeneca and Roche. She writes, “In AstraZeneca we have a new program called Integrative Informatics (i2) establishing the components required to let a linked data cloud grow across R&D. A key component is the URI policy for how to make for example a Clinical Study linkable by giving it a URI, that is a Uniform Resource Identifier, e.g. Read more